Miami SoBe is a beautiful place and not in comparison to other parts of the USA. For a start, you feel the Latino vibe here; Spanish is next to English the key language. Life is outside; during day time at one of the beautiful white beaches, at night at the terraces and on Ocean Drive, the main grid at the ocean.
Gay nightlife is still alive, although the black RnB scene somewhat has taken over SoBe the past couple of years. This does not mean the place is not interesting enough to spend a long weekend (in combination with Orlando or Key West). Just enjoy the glitz and glamour for a couple of days. And maybe you bump into Gloria Esteban (if you still recognize her...).